Bioinformatics Services

The Bioinformatics Unit (BU), led by Júlia Perera, is part of the MARData from the scientific and technical services of the Hospital del Mar Research Insitute. We provide computational support to process high-throughput omics data (eg. NGS, microarrays) with a special focus on translational research. Each type of omics data provides a complementary medical perspective of a biological system or an individual. Therefore, it represents a major opportunity to understand the biological basis of complex diseases, sensitivity and resistance mechanisms to treatments, as well as for the development of predictive biomarkers. We have an extensive background in the field of cancer research but have also been involved in projects related to COVID, chronic urticaria, and major depressive disorder, among other diseases. Our current interest is to integrate multiple NGS data for the detection of patterns/signatures preserved in different pathologies

The facility currently maintains standardized data processing pipelines for NGS analyses (eg. QC, RNASeq, WES, ChIP-Seq, ATAC-Seq, single cell, differential expression), but also performs advanced analysis tailored to each project (eg. predictive algorithms, biomarker discovery, WGCNA, deconvolution, multi-omics integration). Moreover, we can provide training and consultations in bioinformatics, biostatistics and experimental design. You can visit our GitHub page at https://github.com/margenomics.

Research projects

News & activities

Dr. Jana Selent in new Avenues to Developing Personalized Treatments for Schizophrenia

An international study led by the Hospital del Mar Medical Research Institute (Dr. Jana Selent's group of GRIB) has demonstrated, for the first time,...

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Next OPEN GRIB SEMINAR will be given by Helena Crowell

The next Open GRIB Seminar " Whole-transcriptome spatial molecular imaging of Tubullovillous adenomas", by Helena Crowell, will take place next Wednesday 29 May 2024 at 15.30 h in Xipre's room....

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Once again GRIB participates in “Visit the research of La Marató”

At the Hospital del Mar Research Institute, we are participating in this initiative by organizing four visits where different projects funded by the 2021...

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Scientists reveal for the first time the details of protein association at the atomic level

Scientists from the Computational Biophysics group of GRIB (IMIM-UPF) jointly with Freie Universität Berlin (FU Berlin), for the first time, simulated the association and dissociation of protein...

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Animal experimentation in toxicology for the 21st century: needed or outdated?

In this opinion article, Karolina Kopańska, a PhD student in computational toxicology, tells us about her views on chemical risk assessment with new approach...

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PERMANENS: Enabling precision medicine software for personalized suicide risk assessment and management to the emergency department

The Hospital de Mar Research Institute leads this project with the support of partner institutions....

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