Bioinformatics Services

The Bioinformatics Unit (BU), led by Júlia Perera, is part of the MARData from the scientific and technical services of the Hospital del Mar Research Insitute. We provide computational support to process high-throughput omics data (eg. NGS, microarrays) with a special focus on translational research. Each type of omics data provides a complementary medical perspective of a biological system or an individual. Therefore, it represents a major opportunity to understand the biological basis of complex diseases, sensitivity and resistance mechanisms to treatments, as well as for the development of predictive biomarkers. We have an extensive background in the field of cancer research but have also been involved in projects related to COVID, chronic urticaria, and major depressive disorder, among other diseases. Our current interest is to integrate multiple NGS data for the detection of patterns/signatures preserved in different pathologies

The facility currently maintains standardized data processing pipelines for NGS analyses (eg. QC, RNASeq, WES, ChIP-Seq, ATAC-Seq, single cell, differential expression), but also performs advanced analysis tailored to each project (eg. predictive algorithms, biomarker discovery, WGCNA, deconvolution, multi-omics integration). Moreover, we can provide training and consultations in bioinformatics, biostatistics and experimental design. You can visit our GitHub page at https://github.com/margenomics.

Research projects

News & activities

Mar Albà, Ferran sanz and Manuel Pastor in the ranking World’s Top 2% Scientist of Stanford’s University

The new edition of the ranking, which has just been published, includes 41 researchers who have worked at Hospital de Mar and the Research...

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Launch of IHI JU VICT3R Initiative to Revolutionize Nonclinical Drug and Chemical Safety Evaluation with Virtual Controls

VICT3R is a new IHI-funded initiative aiming to revolutionize nonclinical safety testing by significantly reducing animal use in toxicology research....

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Dr. Miguel Ángel Mayer participates in the report on Real World Data and Real World Evidence by the Council for International Organizations of Medical Sciences (CIOMS)

Dr. Miguel ángel Mayer contributed to the CIOMS report on Real World Data and Real World Evidence, guiding regulators on using this data. ...

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Solving the puzzle of membrane receptors

The G-protein-coupled receptor-based drug development group, led by Jana Selent, creates molecular dynamics simulations that help find new drugs for nervous system diseases....

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Prof. Joseph Schacherer as invited speaker at GRIB

Prof. Joseph Schacherer from the University of Strasbourg has done a seminar: "Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation"...

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A study led by GRIB, has identified a group of microproteins exclusive to liver tumors that could be key to developing cancer vaccines

The research was led by the Evolutionary Genomics Research Group at the Hospital del Mar Research Institute, in collaboration with Cima University of Navarra...

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