Research programme on biomedical informatics

GRIB carries out fundamental research and technological developments on the application of new information technologies and computational methods in health and life sciences.

News & activities

GRIB hosts guest researcher Carlo Colantuoni for a seminar and workshop on multi-omics data analysis

GRIB will host Carlo Colantuoni (Johns Hopkins University) on April 21st at PRBB for a seminar and hands-on workshop on multi-omics data analysis. The...

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Broad collaboration produces high-resolution atlas of developing human brain

Johns Hopkins & GRIB researchers have enhanced a cellular road map of how the brain forms and adapts early in life, bringing together nearly...

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Gabriel Santpere co-first author in the new paper published in Nature:”Adaptive evolution of gene regulatory networks in mammalian neocortex”

In the new paper published in Nature:" Adaptive evolution of gene regulatory networks in mammalian neocortex", Gabriel Santpere is the co-first author. The paper...

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New preprint on BioRxiv: “Oncogenes and tumor suppressor genes are enriched in stop-loss mutations generating protein extensions”

The Evolutionary genomics group has done another preprint on bioRxiv. Analysis of stop-loss mutations in > 20,000 cancer samples shows that several oncogenes and...

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GRIB has contributed in a new study:”Human-specific features of the cerebellum and ZP2-regulated synapse development”

This new study, led by Suel-Kee Kim, Adriana Cherskov, and Nenad Sestan, on human-specific cerebellar biology and the unexpected role of ZP2. GRIB has...

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New preprint on BioRxiv by Evolutionary genomics group

A new preprint on bioRxiv: "Evolutionary emergence and preservation of microproteins encoded by upstream ORFs"...

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Research groups

Computational Epigenomics

The Computational Epigenomics group lead by Maria Colomé-Tatché is interested in understanding how different epigenomes...

Microbiome Research

The Microbiome Research Group led by Mireia Valles-Colomer analyses the human body-associated microbial communities (microbiome)...

Comparative and functional genomics

During the last years the genomic revolution has provided unique research opportunities unthought-of before....

Structural Bioinformatics

Led by Baldo Oliva and dedicated to the analysis and modelling of protein 3D structures,...

PharmacoInformatics

Led by Manuel Pastor and focused on development and application of pharmacoinformatic methods in the...

Integrative Biomedical Informatics

Led by Ferran Sanz and dedicated to the generation and execution of research initiatives for...

GPCR Drug Discovery

Led by Jana Selent and focussed on the functionality of G protein coupled receptors (GPCRs)...

Functional Genomics

The research focus of the Functional Genomics group led by Robert Castelo is the development...

Evolutionary genomics

Led by M. Mar Albà and focused on the use of comparative genomics and large-scale...

Neurogenomics

Led by Gabriel Santpere aims to gain insight into the evolutionary mechanisms leading to human...

Computational science

Led by Gianni de Fabritiis is dedicated to computational science in biomedicine and machine learning....

Bioinformatics Services

The Bioinformatics Unit (BU), led by Júlia Perera, is part of the the MARGenomics platform…

About Us

The Research Programme on Biomedical Informatics (GRIB) is a joint research programme of the Hospital del Mar Medical Research Institute (HMRI) and the Department of Medicine and Life Sciences of the Universitat Pompeu Fabra. GRIB brings together a multidisciplinary team of more than seventy scientists, as well as technical and management staff. M. Mar Albà (HMRI) and Manuel Pastor (UPF) are both Coordinators of GRIB.

Work with us

Thank you for your interest in joining our team. We are currently accepting applications for the following positions.